Whole30 Grilled Chicken Sub Sandwich

Indulge in the perfect blend of flavor and nourishment with this Whole30 Grilled Chicken Sub Sandwich—a healthier, gluten-free twist on a classic favorite. Tender, marinated chicken breasts are grilled to perfection with a zesty blend of lemon juice, garlic, and paprika, then layered with fresh tomato, avocado, and crunchy red onion. Instead of traditional bread, crisp romaine lettuce leaves serve as the vessel, offering a light yet satisfying crunch. Topped with Whole30-compliant mayonnaise, this sandwich is a low-carb, paleo-friendly option that doesn’t compromise on taste. Ready in just 35 minutes, this wholesome, dairy-free recipe is perfect for meal prep or a quick lunch bursting with flavor. Whether you’re following the Whole30 program or simply looking for a delicious, guilt-free meal, this grilled chicken lettuce wrap sandwich is sure to become a household favorite!

Nutriscore Rating: 71/100

Prep Time:20 mins

Cook Time:15 mins

Total Time:35 mins

Servings: 4

Ingredients

• 2 pieces boneless skinless chicken breasts
• 2 tablespoons olive oil
• 2 tablespoons lemon juice
• 1 teaspoon garlic powder
• 1 teaspoon onion powder
• 1 teaspoon paprika
• 1 teaspoon salt
• 0.5 teaspoon black pepper
• 8 leaves romaine lettuce leaves
• 1 large tomato
• 0.5 medium red onion
• 1 medium avocado
• 4 tablespoons Whole30 compliant mayonnaise

Directions

Step 1

In a large bowl, mix olive oil, lemon juice, garlic powder, onion powder, paprika, salt, and pepper together.

Step 2

Add the chicken breasts to the marinade and coat them thoroughly. Allow them to marinate for at least 15 minutes at room temperature or up to overnight in the refrigerator.

Step 3

Preheat the grill to medium-high heat.

Step 4

Once marinated, grill the chicken breasts for about 6-7 minutes on each side, or until fully cooked with an internal temperature of 165°F (75°C). Remove from grill and let rest for 5 minutes.

Step 5

While the chicken rests, slice the tomato and red onion thinly. Cut the avocado in half, remove the seed, and slice it thinly.

Step 6

Spread Whole30 compliant mayonnaise on one side of the romaine lettuce leaves.

Step 7

Slice the grilled chicken into strips.

Step 8

To assemble the sandwich, take two romaine leaves and place slices of chicken on one leaf. Top with tomato slices, red onion slices, and avocado slices. Place another lettuce leaf on top to create a sub-style sandwich.

Step 9

Repeat the assembly for the remaining ingredients to create four lettuce-wrapped sub sandwiches.

Step 10

Serve immediately and enjoy!

Nutrition Facts

Serving size	(954.7g)

Amount per serving	% Daily Value*
Calories	1591.4

Total Fat 105.3g	0%
Saturated Fat 16.9g	0%
Polyunsaturated Fat 5.5g
Cholesterol 333.7mg	0%
Sodium 4703.3mg	0%
Total Carbohydrate 46.2g	0%
Dietary Fiber 16.3g	0%
Total Sugars 20.7g
Protein 115.7g	0%

Vitamin D 17.4IU	0%
Calcium 146.0mg	0%
Iron 6.8mg	0%
Potassium 2365.2mg	0%

*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.

Source of Calories

Fat: 59.4%

Protein: 29.0%

Carbs: 11.6%