Upside Down Pepperoni Pizza Casserole

Turn pizza night on its head with this irresistible Upside Down Pepperoni Pizza Casserole! This crowd-pleasing dish takes classic pepperoni pizza flavors and transforms them into a hearty, cheesy casserole that’s perfect for weeknight dinners or casual gatherings. Layers of savory ground Italian sausage, diced vegetables, and rich pizza sauce are topped with gooey mozzarella and cheddar cheeses, then crowned with golden, flaky biscuit dough pieces sprinkled with Italian seasoning and Parmesan. Each bite bursts with comforting pizza goodness, and the upside-down presentation adds a fun twist. Ready in just 45 minutes, this family-friendly recipe is your go-to for all the deliciousness of pizza with the ease of a one-pan casserole. Garnish with fresh basil for a gourmet touch and serve warm for maximum satisfaction!

Nutriscore Rating: 47/100

Prep Time:15 mins

Cook Time:30 mins

Total Time:45 mins

Servings: 6

Ingredients

• 2 tablespoons olive oil
• 1 pound ground Italian sausage
• 1 yellow onion, diced
• 1 red bell pepper, diced
• 2 teaspoons minced garlic
• 2 cups pizza sauce
• 1.5 cups pepperoni slices
• 2 cups shredded mozzarella cheese
• 1 cup shredded cheddar cheese
• 1 16-ounce can refrigerated biscuit dough
• 1 teaspoon dried Italian seasoning
• 0.5 cup grated Parmesan cheese
• 2 tablespoons fresh basil (optional, for garnish)

Directions

Step 1

Preheat your oven to 375°F (190°C). Lightly grease a 9x13-inch baking dish with olive oil or cooking spray.

Step 2

Heat olive oil in a large skillet over medium heat. Add the ground Italian sausage and cook, breaking it up into small pieces, until browned, about 6-8 minutes.

Step 3

Add the diced onion and red bell pepper to the skillet. Cook for 3-4 minutes, or until softened. Stir in the minced garlic and cook for an additional 1 minute until fragrant.

Step 4

Remove the skillet from heat and stir in the pizza sauce. Mix until everything is well combined.

Step 5

Layer 1 cup of pepperoni slices evenly across the bottom of the prepared baking dish. Pour the sausage mixture over the pepperoni, spreading it out evenly.

Step 6

Sprinkle the shredded mozzarella and cheddar cheeses over the sausage mixture. Make sure the cheese covers the entire surface of the dish.

Step 7

Open the can of refrigerated biscuit dough. Separate the biscuits and cut each one into quarters. Arrange the biscuit pieces over the cheese layer, covering the top completely.

Step 8

Sprinkle dried Italian seasoning and grated Parmesan cheese evenly over the biscuit pieces.

Step 9

Bake the casserole in the preheated oven for 25-30 minutes, or until the biscuit topping is golden brown and cooked through.

Step 10

Remove the casserole from the oven and let it cool for 5 minutes. Optionally, garnish with fresh basil before serving.

Step 11

Serve warm and enjoy this fun and flavorful Upside Down Pepperoni Pizza Casserole!

Nutrition Facts

Serving size	(2390.4g)

Amount per serving	% Daily Value*
Calories	6402.0

Total Fat 441.3g	0%
Saturated Fat 190.8g	0%
Polyunsaturated Fat g
Cholesterol 1025.1mg	0%
Sodium 19690.4mg	0%
Total Carbohydrate 315.5g	0%
Dietary Fiber 30.7g	0%
Total Sugars 65.6g
Protein 284.2g	0%

Vitamin D 0IU	0%
Calcium 3443.3mg	0%
Iron 31.9mg	0%
Potassium 6248.3mg	0%

*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.

Source of Calories

Fat: 62.3%

Protein: 17.8%

Carbs: 19.8%