Elevate your weeknight dinner game with this easy and flavorful Salsa Meatloaf recipe, a bold twist on the classic comfort food. Packed with zesty salsa, spices like cumin and chili powder, and tender ground beef, this meatloaf delivers a Tex-Mex-inspired kick in every bite. The tangy-sweet glaze, made from ketchup, brown sugar, and Worcestershire sauce, caramelizes beautifully in the oven, adding a mouthwatering finish. Ready in just 20 minutes of prep and baked to juicy perfection, it’s an effortless dish that pairs perfectly with mashed potatoes, roasted veggies, or a crisp garden salad. Perfect for busy families or meal prepping, this hearty, crowd-pleasing recipe is sure to become a dinnertime favorite. Keywords: salsa meatloaf, Tex-Mex meatloaf recipe, easy meatloaf with salsa, ground beef dinner ideas, weeknight comfort food.
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Preheat your oven to 350°F (175°C). Lightly grease a 9x5-inch loaf pan or line it with parchment paper for easy removal.
In a large mixing bowl, combine the ground beef, salsa, breadcrumbs, eggs, chopped onion, minced garlic, cumin, chili powder, salt, and black pepper. Use your hands or a wooden spoon to mix until just combined—do not overmix.
Transfer the meat mixture into the prepared loaf pan. Press it down gently to form an even layer.
In a small bowl, whisk together the ketchup, brown sugar, and Worcestershire sauce to make the glaze.
Spread the glaze evenly over the top of the meatloaf using a spatula or the back of a spoon.
Place the loaf pan in the preheated oven and bake for 55–60 minutes, or until the internal temperature of the meatloaf reaches 160°F (71°C) using a meat thermometer.
Once done, remove the meatloaf from the oven and let it rest for 10 minutes before slicing. This allows the juices to redistribute for a moist meatloaf.
Slice and serve warm. Pair with mashed potatoes, roasted vegetables, or a side salad for a complete meal.
Serving size | (1624.0g) |
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Amount per serving | % Daily Value* |
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Calories | 2903.1 |
Total Fat 176.8g | 0% |
Saturated Fat 68.5g | 0% |
Polyunsaturated Fat 0g | |
Cholesterol 1014.3mg | 0% |
Sodium 6978.7mg | 0% |
Total Carbohydrate 163.5g | 0% |
Dietary Fiber 13.3g | 0% |
Total Sugars 62.5g | |
Protein 185.8g | 0% |
Vitamin D 82IU | 0% |
Calcium 317.4mg | 0% |
Iron 25.1mg | 0% |
Potassium 3208.8mg | 0% |
Source of Calories