Parmesan Chicken Casserole

Savor the comforting flavors of this creamy and crispy Parmesan Chicken Casserole—a deliciously simple dish that's perfect for busy weeknights or cozy family dinners. Tender chicken breasts are smothered in a rich blend of mayonnaise, sour cream, and Parmesan cheese, enhanced with aromatic spices like garlic powder, onion powder, and Italian seasoning. A buttery panko breadcrumb topping adds an irresistible crunch, baking to golden perfection in just 35 minutes. With minimal prep and a crowd-pleasing flavor profile, this easy casserole is sure to become a go-to favorite. Garnish with fresh parsley for a pop of color and extra freshness, and serve alongside a crisp green salad or garlic bread for a complete meal. Perfect for meal preppers and lovers of hearty, oven-baked dinners!

Nutriscore Rating: 58/100

Prep Time:15 mins

Cook Time:35 mins

Total Time:50 mins

Servings: 6

Ingredients

• 4 pieces chicken breasts
• 1 cup mayonnaise
• 1 cup sour cream
• 1 cup Parmesan cheese, grated
• 1 teaspoon garlic powder
• 1 teaspoon onion powder
• 1 teaspoon dried Italian seasoning
• 0.5 teaspoon salt
• 0.5 teaspoon black pepper
• 1 cup panko breadcrumbs
• 2 tablespoons unsalted butter, melted
• 2 tablespoons fresh parsley, chopped (optional, for garnish)

Directions

Step 1

Preheat your oven to 375°F (190°C) and lightly grease a 9x13-inch casserole dish.

Step 2

Place the chicken breasts into the prepared casserole dish in a single layer.

Step 3

In a mixing bowl, combine the mayonnaise, sour cream, grated Parmesan cheese, garlic powder, onion powder, Italian seasoning, salt, and black pepper. Mix well until creamy and smooth.

Step 4

Evenly spread the mayonnaise mixture over the chicken breasts, ensuring they are well-coated.

Step 5

In a small bowl, mix together the panko breadcrumbs and melted butter until the breadcrumbs are moistened.

Step 6

Sprinkle the breadcrumb mixture evenly over the chicken and mayonnaise mixture.

Step 7

Place the casserole dish in the preheated oven and bake for 30-35 minutes, or until the chicken is fully cooked (internal temperature of 165°F) and the breadcrumb topping is golden brown.

Step 8

Remove the casserole from the oven and let it rest for 5 minutes before serving.

Step 9

Optional: Garnish with freshly chopped parsley for added color and flavor.

Nutrition Facts

Serving size	(1342.3g)

Amount per serving	% Daily Value*
Calories	4067.9

Total Fat 292.4g	0%
Saturated Fat 83.7g	0%
Polyunsaturated Fat g
Cholesterol 1064.3mg	0%
Sodium 4101.2mg	0%
Total Carbohydrate 107.7g	0%
Dietary Fiber 3.3g	0%
Total Sugars 19.1g
Protein 261.8g	0%

Vitamin D 0IU	0%
Calcium 1317.3mg	0%
Iron 8.6mg	0%
Potassium 146.2mg	0%

*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.

Source of Calories

Fat: 64.0%

Protein: 25.5%

Carbs: 10.5%