Oven Fried Spicy Pork Tenderloin Sandwich

Get ready to elevate your sandwich game with this irresistible Oven-Fried Spicy Pork Tenderloin Sandwich! This recipe features tender slices of pork marinated in tangy buttermilk and hot sauce, coated in a perfectly seasoned flour and breadcrumb mixture, and oven-baked to crispy, golden perfection—no deep frying required. Each bite delivers a satisfying crunch, balanced with the zesty heat of paprika and cayenne pepper. Nestle the crispy pork on toasted hamburger buns, then top with creamy coleslaw and optional pickle slices for a delightfully tangy contrast. Perfect for a hearty lunch or casual dinner, this easy-to-make sandwich offers all the indulgence of a fried classic without the extra grease—ideal for those craving bold flavors with a lighter touch!

Nutriscore Rating: 72/100

Prep Time:30 mins

Cook Time:25 mins

Total Time:55 mins

Servings: 4

Ingredients

• 1 lb Pork tenderloin
• 1 cup Buttermilk
• 2 tbsp Hot sauce
• 1 cup All-purpose flour
• 1 cup Breadcrumbs
• 1 tsp Paprika
• 1 tsp Garlic powder
• 0.5 tsp Cayenne pepper
• 1 tsp Salt
• 0.5 tsp Ground black pepper
• 1 as needed Cooking spray
• 4 pieces Hamburger buns
• 1 cup Coleslaw (prepared)
• 4 slices Pickles (optional)

Directions

Step 1

Slice the pork tenderloin into 4 even pieces, then pound each piece to about 1/2-inch thickness using a meat mallet.

Step 2

In a large bowl, combine the buttermilk and 1 tablespoon of the hot sauce. Add the pork slices and marinate in the refrigerator for at least 15 minutes (or up to 2 hours for more flavor).

Step 3

Preheat your oven to 425°F (220°C). Line a baking sheet with parchment paper and place a wire rack on top. Spray the rack lightly with cooking spray to prevent sticking.

Step 4

In a shallow dish, mix together the flour, breadcrumbs, paprika, garlic powder, cayenne pepper, salt, and black pepper.

Step 5

Remove the pork from the buttermilk marinade, letting any excess drip off, and dredge each piece in the breadcrumb-flour mixture, pressing firmly to ensure even coating.

Step 6

Place the coated pork pieces on the prepared wire rack. Lightly spray the tops with cooking spray to encourage browning.

Step 7

Bake in the preheated oven for 20-25 minutes, flipping the pork halfway through, until golden brown and cooked through (internal temperature should reach 145°F).

Step 8

Toast the hamburger buns lightly in the oven or on a skillet.

Step 9

Assemble the sandwiches by placing a piece of crispy pork on the bottom bun. Top with a scoop of coleslaw, a drizzle of the remaining hot sauce (if desired), and pickle slices. Add the top bun and serve immediately.

Nutrition Facts

Serving size	(1571.6g)

Amount per serving	% Daily Value*
Calories	2377.1

Total Fat 72.1g	0%
Saturated Fat 22.9g	0%
Polyunsaturated Fat 2.7g
Cholesterol 347.2mg	0%
Sodium 8938.4mg	0%
Total Carbohydrate 285.8g	0%
Dietary Fiber 70.2g	0%
Total Sugars 48.4g
Protein 207.3g	0%

Vitamin D 163.2IU	0%
Calcium 592.2mg	0%
Iron 23.3mg	0%
Potassium 3208.7mg	0%

*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.

Source of Calories

Fat: 24.8%

Protein: 31.6%

Carbs: 43.6%