Comfort food takes on a Tex-Mex twist with Mom's Turkey Tortilla Casserole, a hearty and flavorful dish perfect for family dinners or using up leftover turkey. This easy-to-make casserole layers tender shredded turkey, tangy salsa, and vibrant diced tomatoes with green chilies, all seasoned with warm notes of chili powder and cumin. Soft corn tortillas and gooey melted Mexican blend cheese tie everything together, creating a delightful medley of textures and flavors. With just 15 minutes of prep time, this casserole bakes to bubbly, golden perfection in under an hour. Garnish with fresh cilantro and a dollop of sour cream for a crowd-pleasing meal that’s as comforting as it is satisfying. Ideal for cozy weeknights, potlucks, or anytime you crave a cheesy, savory dinner!
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Preheat your oven to 375°F (190°C).
In a large skillet, heat olive oil over medium heat. Add the diced onion and cook until softened, about 4-5 minutes.
Stir in the minced garlic, chili powder, and cumin, and cook for an additional 1 minute until fragrant.
Add the canned diced tomatoes with green chilies (undrained), salsa, and shredded turkey. Stir to combine and let simmer for 3-5 minutes. Remove from heat.
Grease a 9x13-inch baking dish with non-stick spray or a little oil.
Spread a thin layer of the turkey mixture on the bottom of the baking dish.
Place two corn tortillas over the turkey mixture, tearing them if necessary to fit and cover the bottom.
Spread a layer of the turkey mixture over the tortillas, followed by a layer of shredded cheese.
Repeat the layering process (tortillas, turkey mixture, cheese) until all ingredients are used, finishing with a top layer of cheese.
Cover the baking dish with aluminum foil and bake in the preheated oven for 20 minutes.
Remove the foil and bake for an additional 10 minutes, or until the cheese is melted and bubbly.
Remove from the oven and let stand for 5 minutes before serving.
Garnish with chopped fresh cilantro, and serve with a dollop of sour cream if desired.
Serving size | (1013.8g) |
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Amount per serving | % Daily Value* |
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Calories | 1369.7 |
Total Fat 99.1g | 0% |
Saturated Fat 54.3g | 0% |
Polyunsaturated Fat 1.5g | |
Cholesterol 260mg | 0% |
Sodium 3735.8mg | 0% |
Total Carbohydrate 53.4g | 0% |
Dietary Fiber 12.1g | 0% |
Total Sugars 25.0g | |
Protein 59.5g | 0% |
Vitamin D 0IU | 0% |
Calcium 1915.5mg | 0% |
Iron 5.8mg | 0% |
Potassium 1657.7mg | 0% |
Source of Calories