Heart-Healthy Homemade Pepperoni Roll

Satisfy your cravings in a guilt-free way with this Heart-Healthy Homemade Pepperoni Roll! Crafted with wholesome whole wheat flour, heart-smart olive oil, and a touch of natural honey, this recipe puts a nutritious spin on a classic favorite. Featuring savory turkey pepperoni, low-fat mozzarella, and aromatic herbs like oregano and garlic powder, each bite delivers rich, comforting flavors without compromising on health. The dough is lovingly kneaded and baked to golden perfection, creating a crisp crust and soft, airy interior. Perfect for family dinners, meal prep, or game-day snacks, this easy-to-make pepperoni roll is packed with protein, fiber, and all the nostalgic charm of a traditional recipe—just a little lighter! Perfectly customizable and easy to slice, it’s a must-try for fans of healthy comfort food.

Nutriscore Rating: 67/100

Prep Time:20 mins

Cook Time:25 mins

Total Time:45 mins

Servings: 8

Ingredients

• 3 cups whole wheat flour
• 1 package instant yeast
• 1.25 cups warm water
• 3 tablespoons olive oil
• 2 tablespoons honey
• 1 cup turkey pepperoni slices
• 1 cup low-fat mozzarella cheese, shredded
• 0.5 teaspoon salt
• 1 teaspoon dried oregano
• 0.5 teaspoon garlic powder
• 0 nonstick cooking spray

Directions

Step 1

In a large bowl, combine the whole wheat flour, instant yeast, and salt. Stir to mix evenly.

Step 2

In a separate bowl, combine warm water, olive oil, and honey. Stir until the honey is completely dissolved.

Step 3

Gradually add the wet ingredients into the dry ingredients and mix until a dough forms.

Step 4

Knead the dough on a floured surface for about 5-7 minutes until it is smooth and elastic.

Step 5

Place the dough in a lightly oiled bowl, cover with a towel, and let it rise in a warm place for about 1 hour or until it has doubled in size.

Step 6

Preheat your oven to 375°F (190°C).

Step 7

Once the dough has risen, punch it down to remove air bubbles, then roll it out into a rectangle about 12x18 inches on a floured surface.

Step 8

Sprinkle the dough evenly with dried oregano and garlic powder.

Step 9

Layer the turkey pepperoni slices and shredded low-fat mozzarella cheese over the rectangle of dough, leaving a 1-inch border on all sides.

Step 10

Begin rolling the dough tightly from one of the long edges, sealing the ends by pinching the dough.

Step 11

Spray a baking sheet with nonstick cooking spray and place the roll on it, seam side down.

Step 12

Using a sharp knife, make shallow diagonal slashes across the top of the roll without cutting all the way through the dough.

Step 13

Let the roll rest for an additional 10 minutes.

Step 14

Bake in the preheated oven for 25 minutes or until the roll is golden brown.

Step 15

Allow the pepperoni roll to cool for a few minutes before slicing and serving.

Nutrition Facts

Serving size	(1105.8g)

Amount per serving	% Daily Value*
Calories	2638.4

Total Fat 101.1g	0%
Saturated Fat 32.4g	0%
Polyunsaturated Fat 4.0g
Cholesterol 314.2mg	0%
Sodium 6161.2mg	0%
Total Carbohydrate 312.7g	0%
Dietary Fiber 46.2g	0%
Total Sugars 40.2g
Protein 151.3g	0%

Vitamin D 0IU	0%
Calcium 1111.7mg	0%
Iron 20.1mg	0%
Potassium 2508.8mg	0%

*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.

Source of Calories

Fat: 32.9%

Protein: 21.9%

Carbs: 45.2%