Warm, comforting, and perfect for busy weeknights, this Chicken and Biscuit Casserole brings together the best of hearty home-cooked meals in one dish. Featuring tender shredded chicken, a medley of colorful mixed vegetables, and a creamy, flavor-packed base made with cream of chicken soup and sour cream, this casserole is topped with golden, fluffy biscuits that bake right in the oven. With just 20 minutes of prep time, it’s an easy and satisfying dinner option that the whole family will love. The biscuit topping, made from Bisquick or baking mix, adds a buttery, flaky layer that perfectly complements the savory filling below. Ideal for weeknight dinners or cozy gatherings, serve this casserole with a crisp side salad or roasted veggies for a complete, crowd-pleasing meal.
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Preheat your oven to 375°F (190°C). Grease a 9x13-inch baking dish and set aside.
In a large mixing bowl, combine the shredded chicken, frozen mixed vegetables, cream of chicken soup, chicken broth, sour cream, garlic powder, onion powder, salt, and black pepper. Mix thoroughly to combine.
Pour the chicken and vegetable mixture into the prepared baking dish, spreading it out evenly.
In a separate bowl, combine the Bisquick mix, milk, and melted butter. Stir until a soft dough forms.
Drop spoonfuls of the biscuit dough evenly over the chicken mixture in the baking dish. Do not worry if the dough does not completely cover the top; it will spread as it bakes.
Place the casserole in the preheated oven and bake for 30 to 35 minutes, or until the biscuits are golden brown and the filling is bubbling.
Remove the casserole from the oven and let it cool for 5 minutes before serving.
Serve warm and enjoy this cozy, satisfying dish with your favorite side salad or steamed vegetables.
Serving size | (2048.4g) |
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Amount per serving | % Daily Value* |
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Calories | 2739.7 |
Total Fat 103.1g | 0% |
Saturated Fat 47.4g | 0% |
Polyunsaturated Fat 1.8g | |
Cholesterol 763.2mg | 0% |
Sodium 5176.2mg | 0% |
Total Carbohydrate 175.7g | 0% |
Dietary Fiber 17.3g | 0% |
Total Sugars 50.1g | |
Protein 263.1g | 0% |
Vitamin D 126.9IU | 0% |
Calcium 1095.3mg | 0% |
Iron 18.6mg | 0% |
Potassium 3555.9mg | 0% |
Source of Calories